Tirzepatide combines the actions of two hormones: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). It is primarily used for the treatment of type 2 diabetes.
GLP-1 and GIP are naturally occurring hormones produced in the gut that play important roles in regulating blood sugar levels, insulin secretion, and appetite.By activating receptors, tirzepatide enhances insulin secretion and helps to lower blood glucose levels. It also reduces the release of glucagon, a hormone that raises blood sugar levels.
Tirzepatide has the additional benefit of slowing down gastric emptying, which can help regulate digestion and contribute to feelings of fullness and reduced appetite. This effect can be helpful for individuals who are aiming to manage their weight.