Compounded Sublingual Semaglutide: Proper Administration, Storage, and Use

How To Take Your Medication

To ensure the effectiveness of your compounded sublingual semaglutide suspension, follow these steps carefully:

  1. Check Your Dosage – Confirm the prescribed dosing volume (in mL) before administration.
  2. Draw Up Your Dose
    • Insert the oral syringe into the bottle adapter.
    • Pull back the syringe plunger to draw up the correct amount of liquid (in mL) as prescribed by your healthcare provider.
  3. Administer Under the Tongue
    • Place the measured dose directly under your tongue.
    • Do not swallow immediately. Hold the liquid under your tongue for at least 60 seconds before swallowing.
    • Avoid talking while holding the medication under your tongue to ensure proper absorption.
  4. Post-Dose Care
    • Do not eat, drink, or brush your teeth for at least 30 minutes after taking your dose.
    • Taking your medication at night after brushing and flossing may help integrate it into your routine.

Storage Instructions

  • Store your compounded sublingual semaglutide suspension at room temperature.
  • Ensure the bottle is tightly closed when not in use.
  • Check the beyond-use-date (BUD) on the bottle. Do not use past this date.
  • Keep out of reach of children and pets.

Why Proper Administration Is Important

  • The sublingual (under-the-tongue) absorption method allows the medication to enter your bloodstream directly, bypassing the digestive system.
  • Swallowing too soon or consuming food or drinks too early can reduce the medication’s absorption.

Last Updated: 03/04/2025